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Southeast Cancer Control Consortium, Inc.

Clinical Trials

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Protocol Number Study Title

CTSU Z6051
A Phase III Prospective Randomized Trial Comparing Laparoscopic-assisted Resection Versus Open Resection for Rectal Cancer

HLMCC 0501
non-Hispanic/Latino Arm closed 9/21/07
Stress Management Training for Patients Undergoing Chemotherapy

HLMCC 0502
Thyroid function & breast cancer: A pilot study to estimate the prevalence of thyroid dysfunction in women diagnosed with breast cancer and the magnitude of change in thyroid function post-chemotherapy

HLMCC 0806
Phase II Placebo-Controlled Trial of Lisinopril and Coreg to Reduce
Cardiotoxicity in Patients With Breast Cancer Receiving (Neo)Adjuvant Chemotherapy With Trastuzumab (Herceptin)

MA.27B
The Influence of Five Years of Adjuvant Anastrozole or Exemestane
on Bone Mineral Density (Bmd) in Postmenopausal Women
with Primary Breast Cancer

NSABP B-41
A Randomized Phase III Trial of Neoadjuvant Therapy for Patients with Palpable and Operable HER2-Positive Breast Cancer Comparing the Combination of Trastuzumab Plus Lapatinib to Trastuzumab and to Lapatinib Administered with Weekly Paclitaxel Following AC Accompanied by Correlative Science Studies to Identify Predictors of Pathologic Complete Response

NSABP B-43
A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy

NSABP B-44-I (BETH)
A Multicenter Phase III Randomized Trial of Adjuvant Therapy for Patients with HER2-Positive Node-Positive or High Risk Node-Negative Breast Cancer Comparing Chemotherapy Plus Trastuzumab with Chemotherapy
Plus Trastuzumab Plus Bevacizumab

NSABP B46-I
A Phase III Clinical Trial Comparing the Combination of TC Plus Bevacizumab to
TC Alone and to TAC for Women with Node-Positive or High-Risk Node-Negative,
HER2-Negative Breast Cancer

NSABP BP-59
Bone Marrow Analysis in Early-Stage Breast Cancer

NSABP FB-6
A Phase II Clinical Trial of Four Cycles of Doxorubicin and Cyclophosphamide Followed by Weekly Paclitaxel Given Concurrently with Pazopanib as Neoadjuvant Therapy Followed by Postoperative Pazopanib for Women with Locally Advanced Breast Cancer

NSABP P-5
Statin Polyp Prevention Trial in Patients with Resected Colon Cancer


RTOG 0232
A Phase III Study Comparing Combined External Beam Radiation and Transperineal Interstitial Permanent Brachytherapy with Brachytherapy alone for Selected Patients with Intermediate Risk Prostatic Carcinoma

RTOG 0413
Clos to lo-risk women 12/30/06
A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) Versus Partial Breast Irradiation (PBI) for Women with Stage 0, I, or II Breast Cancer

RTOG 0421
A Phase III Trial for Locally Recurrent, Previously Irradiated Head and Neck Cancer: Concurrent Reirradiation and Chemotherapy Versus Chemotherapy Alone

RTOG 0433
A Phase III International Randomized Trial of Single Versus Multiple Fractions for
Re-Irradiation of Painful Bone Metastases

RTOG 0436
A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients With Esophageal Cancer Who Are Treated Without Surgery

RTOG 0517
Randomized Phase III Trial to Evaluate Radiopharmaceuticals and Zoledronic Acid in the Palliation of Osteoblastic Metastases from
Lung, Breast, and Prostate Cancer

RTOG 0522
A Randomized Phase III Trial of Concurrent Accelerated Radiation and Cisplatin Versus Concurrent Accelerated Radiation, Cisplatin, and Cetuximab (C225) [Followed by Surgery for Selected Patients] for Stage III and IV Head and Neck Carcinomas

RTOG 0524
A Phase I/II Trial of a Combination of Paclitaxel and Trastuzumab with Daily Irradiation or Paclitaxel Alone with Daily Irradiation Following Transurethral Surgery for Non-Cystectomy Candidates with Muscle-Invasive Bladder Cancer

RTOG 0534
A Phase III Trial Of Short Term Androgen Deprivation With Pelvic Lymph Node Or Prostate Bed Only Radiotherapy (SPORT) In Prostate Cancer Patients With A Rising PSA After Radical Prostatectomy

RTOG 0537
Phase II closed 10/23/09
Phase III OPEN
A Phase II/III Study Comparing Acupuncture-like Transcutaneous Electrical Nerve Stimulation (ALTENS) Versus Pilocarpine in Treating Early Radiation-Induced Xerostomia

RTOG 0539
Phase II Trial of Observation for Low-Risk Meningiomas and of Radiotherapy for Intermediate- and High-Risk Meningiomas


RTOG 0612
INVESTIGATING MARKERS OF RADIATION OUTCOME IN PATIENTS WITH INTERMEDIATE-RISK PROSTATE CANCER USING DNA MICROARRAY ANALYSIS:
AN RTOG PILOT STUDY

RTOG 0617
A Randomized Phase III Comparison Of Standard- Dose (60 Gy) Versus High-Dose (74 Gy) Conformal Radiotherapy With Concurrent And Consolidation Carboplatin/Paclitaxel In Patients With Stage IIIA/IIIB Non-Small Cell Lung Cancer
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Phone: (336) 777-3036 Fax: (336) 777-3177 Email: scccinfo@wfubmc.edu
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